Other notable boxers that challenged Little Mac were King Hippo and Japanese boxer Piston Honda. Sandman, and Super Macho Man make their appearances in this game. Having Doc Louis, a retired pro boxer and former heavyweight champion, as his boxing coach, Little Mac trained day and night for the challenges in the ring. Little Mac was no taller than 5 feet, and barely weighed over 100 pounds, but his ultimate dream was to become the heavyweight champion of the World Video Boxing Association ( WVBA). Because this is the only Punch-Out game where the controlled boxer has a name, all Punch-Out!! games onward have dubbed the main challenger the name of Little Mac. This is the game where Little Mac gets his name and his background. In 1987, Mike Tyson's Punch-Out!! was released, and this marked the first game where the challenger whom the player controls gained an identity. Little Mac (right) and his trainer Doc Louis as seen in the original NES game.

Punch Out series Mike Tyson's Punch-Out!!